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HEPATITIS C VIRUS (HCV): Surface spikes represent the E (Envelope) Proteins. Each spike is a dimer of E1 and E2 anchored into the viral envelope. Viral envelope is derived from host cell ER membrane. Beneath the envelope lies the core which houses the RNA genome. HCV is a small enveloped + single stranded RNA virus. It classified in the family Flaviviridae (L. Flavus: yellow named after Yellow Fever) in the genus Hepacivirus. |